KMID : 0032220100220040422
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Annals of Dermatology 2010 Volume.22 No. 4 p.422 ~ p.425
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A Case of Pyoderma Gangrenosum with Ulcerative Colitis Treated with Mesalazine
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Lee Jae-In
Park Hyun-Jeong Lee Jun-Young Cho Baik-Kee
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Abstract
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Pyoderma gangrenosum (PG) manifests as recurrent deep ulceration of the skin and PG is associated with a variety of disorders. Approximately 30% of the cases of PG develop in patients with inflammatory bowel disease. A 34-year-old woman presented with a one-week history of recurrent ulcers on the right cheek and back. She was diagnosed with ulcerative colitis (UC) 4 years previously and with PG 1 year previously. The clinical course of the skin lesions followed the status of her UC. The patient¡¯s skin lesions and bowel symptoms were not improved with prednisolone. After she was started on mesalazine, we observed rapid resolution of skin lesions and bowel symptoms. Herein, we report a case of recurrent PG with UC, and we discuss the possible association between these two conditions, and the efficacy of mesalazine therapy for the treatment of PG combined with UC.
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KEYWORD
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Mesalazine, Pyoderma gangrenosum, Ulcerative colitis
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